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Head of Group
Director of Corporate Program
His main research interests are ligand- and structure-based drug design with focus on transmembrane transport proteins, prediction of on- and off-kinetics, as well as semantic data integration.
Publications
Showing entries 6 - 10 out of 326
Helmke, PS & Ecker, GF 2025, 'Refining Drug-Induced Cholestasis Prediction: An Explainable Consensus Model Integrating Chemical and Biological Fingerprints', Journal of Chemical Information and Modeling, vol. 65, no. 11, pp. 5301-5316. https://doi.org/10.1021/acs.jcim.4c02363
Goldmann, U, Wiedmer, T, Garofoli, A, Sedlyarov, V, Bichler, M, Haladik, B, Wolf, G, Christodoulaki, E, Ingles-Prieto, A, Ferrada, E, Frommelt, F, Teoh, ST, Leippe, P, Onea, G, Pfeifer, M, Kohlbrenner, M, Chang, L, Selzer, P, Reinhardt, J, Digles, D, Ecker, GF, Osthushenrich, T, MacNamara, A, Malarstig, A, Hepworth, D & Superti-Furga, G 2025, 'Data- and knowledge-derived functional landscape of human solute carriers', Molecular Systems Biology, vol. 21, no. 6, 33, pp. 599-631. https://doi.org/10.1038/s44320-025-00108-2
Mazoudji, A & Ecker, GF 2025, 'Docking-Based Classification of SGLT2 Inhibitors', Molecules (Basel, Switzerland), vol. 30, no. 10. https://doi.org/10.3390/molecules30102179
Smajić, A, Steger-Hartmann, T, Ecker, GF & Hackl, A 2025, 'Data Exploration for Target Predictions Using Proprietary and Publicly Available Data Sets', Chemical Research in Toxicology, vol. 38, no. 5, pp. 820-833. https://doi.org/10.1021/acs.chemrestox.4c00347
Dreier, D, Belleza, OJV, Schlögl, K, Kickinger, S, Hellsberg, E, Mayer, FP, Sandtner, W, Mikšovsky, P, Schittmayer, M, Hu, Y, Jäntsch, K, Holy, M, Ecker, GF, Sitte, HH & Mihovilovic, MD 2025, 'Careful Examination of a Novel Azobenzene Paroxetine Derivative and Its Interactions With Biogenic Amine Transporters', Journal of Neurochemistry, vol. 169, no. 4, e70068. https://doi.org/10.1111/jnc.70068
Projects
Molecular Drug Targets
Hering, S. (Project Lead), Ecker, G. (Co-Lead), Maulide, N. (Co-Lead), Weinzinger, A. (Co-Lead) & Gonzalez Herrero, L. (Co-Lead)
1/12/10 → 31/12/22
Project: Research funding