Finished Projects
- eTOX - "A better prediction of toxic effects of new drug candidates":
- Integrating bioinformatics and chemoinformatics approaches for the development of expert systems allowing the in silico prediction of toxicities.
- eTRANSAFE - "Enhancing TRANslational SAFEty Assessment through Integrative Knowledge Management":
- Based on previous experience, the eTRANSAFE project proposes a state-of-the-art, powerful and flexible technical architecture for the data sharing, integration and exploitation.
- EU-ToxRisk - "An Integrated European 'Flagship' Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century":
- toxicological assessment based on human cell responses and a comprehensive mechanistic understanding of cause-consequence relationships of chemical adverse effects.
- FAIRness - "for Life Science Data in Austria"
- FAIR principles for data (Findable, Accessible, Interoperable, Reuseable)
- K4DD - "Kinetics for Drug Discovery":
- The goal of the K4DD project was to improve our understanding of how potential drugs bind with their target, and develop methods and tools to allow researchers to study drug-target interactions with greater ease.
- Ligands for the GABAA receptor alpha+ / beta- interface
- The project goal was the development and testing of substance libraries which act at a recently described (modulatory alpha+/ beta-) binding site of GABAA (gamma-aminobutyric acid type A) receptors.
- MolTag - "Molecular Drug Targets":
- PhD/doctoral program in pharmaceutical sciences, funded by the Austrian Science Fund.
- Open PHACTS - "Open Pharmacological Concepts Triple Store":
- The Open PHACTS consortium reduced the barriers to drug discovery by applying semantic technologies to available data resources, creating an Open Pharmacological Space.
- ReSOLUTE - "Research Empowerment on Solute Carriers":
- The goal of the project is to intensify worldwide research on solute carriers (SLCs), a relatively understudied group of proteins that control essential physiological functions, and potentially establish them as a novel target class for medicine research and development.
- REsolution - "Medical Genetic Solutions for RESOLUTE":
- REsolution aims at gathering publicly available datasets and combining them with novel experimental data on genetic variants of SLCs. To that end, REsolution will build on the ongoing project RESOLUTE.
- SFB35 - "Transmembrane Transporters in Health and Disease":
- Sonderforschungsbereich (research cluster) funded by the Austrian Science Fund (FWF).
- TransQST - "Translational quantitative systems toxicology to improve the understanding of the safety of medicines":
- The focus of the TransQST project will be to provide innovative methodologies and software tools for systems toxicology modelling.