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Head of Group
Dean of the Faculty of Life Sciences
Director of Corporate Program

His main research interests are ligand- and structure-based drug design with focus on transmembrane transport proteins, prediction of on- and off-kinetics, as well as semantic data integration.

Sprechstunde für Studierende

  • Montags 13:00 - 14:00 Uhr, Raum 2E405 oder online
  • nur nach Terminvereinbarung: per E-Mail mindestens 3 Tage im Voraus!

Contact Hours for Students

  • Mondays 13:00 - 14:00, Room 2E405 or online
  • only by appointment: arrange via E-Mail at least 3 days in advance!
Publications

Showing entries 1 - 5 out of 292

Brecklinghaus, T, Albrecht, W, Kappenberg, F, Duda, J, Vartak, N, Edlund, K, Marchan, R, Ghallab, A, Cadenas, C, Günther, G, Leist, M, Zhang, M, Gardner, I, Reinders, J, Russel, FGM, Foster, AJ, Williams, DP, Damle-Vartak, A, Grandits, M, Ecker, G, Kittana, N, Rahnenführer, J & Hengstler, JG 2022, 'The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds', Chemico-Biological Interactions, vol. 351, 109728. doi.org/10.1016/j.cbi.2021.109728


Loser, D, Grillberger, K, Hinojosa, MG, Blum, J, Haufe, Y, Danker, T, Johansson, Y, Möller, C, Nicke, A, Bennekou, SH, Gardner, I, Bauch, C, Walker, P, Forsby, A, Ecker, GF, Kraushaar, U & Leist, M 2021, 'Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signaling', Archives of Toxicology, vol. 95, no. 12, pp. 3695-3716. doi.org/10.1007/s00204-021-03168-z


Kickinger, S, Lie, MEK, Suemasa, A, Al-Khawaja, A, Fujiwara, K, Watanabe, M, Wilhelmsen, KS, Falk-Petersen, CB, Frølund, B, Shuto, S, Ecker, GF & Wellendorph, P 2021, 'Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT1', Frontiers in Chemistry, vol. 9, 736457. doi.org/10.3389/fchem.2021.736457


Van der Stel, W, Carta, G, Eakins, J, Delp, J, Suciu, I, Forsby, A, Cediel-Ulloa, A, Attoff, K, Troger, F, Kamp, H, Gardner, I, Zdrazil, B, Moné, MJ, Ecker, GF, Pastor, M, Gómez-Tamayo, JC, White, A, Danen, EHJ, Leist, M, Walker, P, Jennings, P, Hougaard Bennekou, S & Van de Water, B 2021, 'New approach methods supporting read-across: Two neurotoxicity AOP-based IATA case studies', Altex. doi.org/10.14573/altex.2103051


Loser, D, Hinojosa, MG, Blum, J, Schaefer, J, Brüll, M, Johansson, Y, Suciu, I, Grillberger, K, Danker, T, Möller, C, Gardner, I, Ecker, GF, Bennekou, SH, Forsby, A, Kraushaar, U & Leist, M 2021, 'Functional alterations by a subgroup of neonicotinoid pesticides in human dopaminergic neurons', Archives of Toxicology, vol. 95, no. 6, pp. 2081-2107. doi.org/10.1007/s00204-021-03031-1


Activities

Showing entries 1 - 5 out of 136

Arzneistoffentwicklung in Zeiten personalisierter Medizin

Gerhard Ecker
APOKongress - Personalisierte Medizin und Pharmazie
Conference, Talk or oral contribution
19.6.2021 - 19.6.2021

In silico Toxicology - from prediction of transporter interaction profiles to toxicological read across and beyond

Gerhard Ecker
XII EWDD - 12th European Workshop in Drug Design
Conference, Talk or oral contribution
20.5.2019 - 20.5.2019

Research of new TTK kinase inhibitors by using structure-based pharmacophore modelling and docking experiments

Riccardo Martini , Katharina Schwartz , Gerhard Ecker
XII EWDD - 12th European Workshop in Drug Design
Conference, Poster presentation
19.5.2019 - 19.5.2019

The OMICS approach - the buzz that makes the world go round

Gerhard Ecker
24th EAHP Congress
Conference, Talk or oral contribution
27.3.2019 - 27.3.2019

From unique protein identifiers to a selected pool of structures: Knime used as a mean to retrieve, analyze, interactively select and download protein 3D shapes

Riccardo Martini , Giulia Banci , Gerhard Ecker
KNIME Spring Summit 2019
Conference, Poster presentation
20.3.2019 - 20.3.2019