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Head of Group
Director of Corporate Program
His main research interests are ligand- and structure-based drug design with focus on transmembrane transport proteins, prediction of on- and off-kinetics, as well as semantic data integration.
Publications
Showing entries 171 - 175 out of 312
Sarker, S, Weissensteiner, R, Steiner, IM, Sitte, HH, Ecker, G, Freissmuth, M & Sucic, S 2010, 'The High-Affinity Binding Site for Tricyclic Antidepressants Resides in the Outer Vestibule of the Serotonin Transporter', Molecular Pharmacology, vol. 78, no. 6, pp. 1026-1035. https://doi.org/10.1124/mol.110.067538
Klepsch, F, Stockner, T, Erker, T, Müller, M, Chiba, P & Ecker, G 2010, 'Using Structural and Mechanistic Information to Design Novel Inhibitors/Substrates of P-Glycoprotein', Current Topics in Medicinal Chemistry, vol. 10, no. 17, pp. 1769-1774. https://doi.org/10.2174/156802610792928004
Fürst, R, Nowikow, C, Berenyi, A, Ecker, GF, Schmid, W, Zupko, I & Rinner, DIU 2010, 'Synthesis and biological evaluation of novel carbocycle-containing combretastatin A-4 analogs', American Chemical Society. Abstracts of Papers (at the National Meeting), vol. 240.
Sugano, K, Kansy, M, Artursson, P, Avdeef, A, Bendels, S, Di, L, Ecker, GF, Faller, B, Fischer, H, Gerebtzoff, G, Lennernaes, H & Senner, F 2010, 'Coexistence of passive and carrier-mediated processes in drug transport', Nature Reviews. Drug Discovery, vol. 9, no. 8, pp. 597-614. https://doi.org/10.1038/nrd3187
Ecker, GF 2010, 'MedChemComm in partnership with the European Federation for Medicinal Chemistry', MedChemComm, vol. 1, no. 1, pp. 12-12. https://doi.org/10.1039/c0md90003f
Activities
Showing entries 1 - 5 out of 202
In silica prediction of toxicity - from QSAR models to biological fingerprinting
Gerhard Ecker
AAPR 23 - patterns in one health
Conference,
Talk or oral contribution
25.10.2023 - 25.10.2023
Predicting chemicals' Molecular Initiating Events (MIEs) based on protein structure
Gerhard Ecker
ASPIS Open Symposium
Conference,
Talk or oral contribution
25.11.2022 - 25.11.2022
Structure-based prediction of molecular initiating events - where are we?
Gerhard Ecker
3rd In silico Toxicology Conference 2022
Conference,
Talk or oral contribution
29.9.2022 - 29.9.2022
Transporter Informatics and Computational Toxicology - from QSAR to Machine Learning and beyond
Gerhard Ecker
Advanced summer School in Drug Research and Development
Summer/Winter school,
Talk or oral contribution
7.9.2022 - 7.9.2022
Hypothesis generation for variant effects using a KNIME workflow for automatic mapping of disease-related mutations onto 3D protein structures
Jiahui Huang
,
Claire Colas
,
Gerhard Ecker
ACS Fall 2022
Conference,
Poster presentation
21.8.2022 - 21.8.2022