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Head of Group
Director of Corporate Program
His main research interests are ligand- and structure-based drug design with focus on transmembrane transport proteins, prediction of on- and off-kinetics, as well as semantic data integration.
Publications
Showing entries 1 - 5 out of 326
Juhás, M & Ecker, G 2026, 'A Proteochemometric Model for Ligands of the SLC5 Transporter Family', Archiv der Pharmazie, vol. 359, no. 1, pp. e70183. https://doi.org/10.1002/ardp.70183
Grillberger, K, Magel, V, Leist, M & Ecker, GF 2025, 'Leveraging Consensus Docking Approaches for Human Mitochondrial Complexes I and III', Chemical Research in Toxicology. https://doi.org/10.1021/acs.chemrestox.5c00348
Helmke, PS, Kandler, J, Ilie, S, Gaskin, L & Ecker, GF 2025, 'Data-driven assessment of bioisosteric replacements and their influence on off-target activity profiles', RSC Medicinal Chemistry, vol. 16, no. 12, pp. 6048-6058. https://doi.org/10.1039/d5md00686d
Bloothooft, M, Huang, J, Hamze, M, Houtman, MJC, de Boer, TP, van Hasselt, PM, Ecker, GF, Porcher, C, Medina, I & van der Heyden, MAG 2025, 'Exploring the Cell Biological and Functional Effects of the First Disease Associated KCC1 Genetic Variant', Journal of Cellular Physiology, vol. 240, no. 12, pp. e70124. https://doi.org/10.1002/jcp.70124
Vlasveld, M, van den Berk, L, Piñero, J, Helmke, PS, Ecker, GF, van Rossom, R, Schmidt, BZ, Verfaillie, C, Tassis, K, Callegaro, G, Bouwman, P & van de Water, B 2025, 'A broad kinase inhibitor library live cell imaging screen using liver, kidney and cardiac hiPSC-ICAM1-eGFP reporter lineages identifies liabilities for TNFα pathway modulation', Archives of Toxicology. https://doi.org/10.1007/s00204-025-04226-6
Activities
Showing entries 31 - 35 out of 207
Leveraging linked open data - from transporter interaction profiling to toxicity prediction and beyond
Gerhard Ecker
Janssen internal computational chemistry meeting
Lecture series, colloquium,
Talk or oral contribution
15.3.2017 - 15.3.2017
Exploiting semantically integrated life science data - from transporter profiling to toxicity prediction
Gerhard Ecker
1st MuTaLig COST Action Training School
Summer/Winter school,
Talk or oral contribution
9.2.2017 - 9.2.2017
The power of open data - linking transporter interaction profiles to in vivo toxicity
Gerhard Ecker
Talk or oral contribution
3.2.2017 - 3.2.2017
Leveraging linked open data - from transporter interaction profiles to toxicity prediction
Gerhard Ecker
Talk or oral contribution
19.1.2017 - 19.1.2017
Open Innovation in the Age of Big Data
Gerhard Ecker
Open Innovation
Conference,
Talk or oral contribution
17.11.2016 - 17.11.2016