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Head of Group
Director of Corporate Program
His main research interests are ligand- and structure-based drug design with focus on transmembrane transport proteins, prediction of on- and off-kinetics, as well as semantic data integration.
Publications
Showing entries 1 - 5 out of 312
Li, E, Boujeddaine, N, Houtman, MJC, Maas, Sluijter, , Ecker, G, Weinzinger, A, van Ham, W & van der Heyden, M 2024, 'Development of new Kir2.1 channel openers from propafenone analogues', British Journal of Pharmacology. <https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17377>
Digles, D, Ingles-Prieto, A, Dvorak, V, Mocking, TAM, Goldmann, U, Garofoli, A, Homan, EJ, Di Silvio, A, Azzollini, L, Sassone, F, Fogazza, M, Bärenz, F, Pommereau, A, Zuschlag, Y, Ooms, JF, Tranberg-Jensen, J, Hansen, JS, Stanka, J, Sijben, HJ, Batoulis, H, Bender, E, Martini, R, IJzerman, AP, Sauer, DB, Heitman, LH, Manolova, V, Reinhardt, J, Ehrmann, A, Leippe, P, Ecker, GF, Huber, KVM, Licher, T, Scarabottolo, L, Wiedmer, T & Superti-Furga, G 2024, 'Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily', Frontiers in Pharmacology, vol. 15, 1401599. https://doi.org/10.3389/fphar.2024.1401599
Granulo, N, Sosnin, S, Digles, D & Ecker, GF 2024, 'The macrocycle inhibitor landscape of SLC‐transporter', Molecular Informatics, vol. 43, no. 5, e202300287. https://doi.org/10.1002/minf.202300287
Huang, J, Osthushenrich, T, MacNamara, A, Mälarstig, A, Brocchetti, S, Bradberry, S, Scarabottolo, L, Ferrada, E, Sosnin, S, Digles, D, Superti-Furga, G & Ecker, GF 2024, 'ProteoMutaMetrics: machine learning approaches for solute carrier family 6 mutation pathogenicity prediction', Rsc advances, vol. 14, no. 19, 00748, pp. 13083-13094. https://doi.org/10.1039/d4ra00748d
Ferrada, E, Wiedmer, T, Wang, WA, Frommelt, F, Steurer, B, Klimek, C, Lindinger, S, Osthushenrich, T, Garofoli, A, Brocchetti, S, Bradberry, S, Huang, J, MacNamara, A, Scarabottolo, L, Ecker, GF, Malarstig, A & Superti-Furga, G 2024, 'Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8', Journal of Molecular Biology, vol. 436, no. 2, 168383. https://doi.org/10.1016/j.jmb.2023.168383
Activities
Showing entries 196 - 200 out of 202
P_VSA descriptors: a proper tool to predict P-glycoprotein inhibitor activity
Wolfgang Holzer
,
Gerhard Ecker
,
Peter Chiba
19. Wissenschaftliche Tagung der Österreichischen Pharmazeutischen Gesellschaft, Innsbruck 2006
Conference,
Poster presentation
..2006 - ..2006
Recent Results in the Alcoholic Aziridine Cleavage
Winfried Neuhaus
,
Silvester Ölzant
,
Urs Peter Fringeli
,
Gerhard Ecker
,
Christian Noe
1st European Chemistry Conference
Conference,
Poster presentation
..2006 - ..2006
Role of transmembrane domain/transmembrane domain interfaces of P-glycoprotein in solute transport
Gerhard Ecker
,
Peter Chiba
,
Sandra Pferschy
,
Stephan Kopp
FEBS Special Meeting ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Disease
Conference,
Poster presentation
..2006 - ..2006
Shape similarity values as tool for QSAR studies on inhibitors of P-glycoprotein
Gerhard Ecker
,
Elisabet Gregori
,
Peter Chiba
,
Ferran Sanz
,
Jordi Mestres
,
Stephan Kopp
231st American Chemical Society National Meeting
Conference,
Poster presentation
..2006 - ..2006
Similarity calculations on MDR-modulators for establishment of quantitative structure acticity relationships
Gerhard Ecker
,
Ferran Sanz
,
Jordi Mestres
ESMEC - European School of Medicinal Chemistry
Summer/Winter school,
Poster presentation
..2006 - ..2006