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Head of Group
Director of Corporate Program
His main research interests are ligand- and structure-based drug design with focus on transmembrane transport proteins, prediction of on- and off-kinetics, as well as semantic data integration.
Publications
Showing entries 1 - 5 out of 312
Li, E, Boujeddaine, N, Houtman, MJC, Maas, Sluijter, , Ecker, G, Weinzinger, A, van Ham, W & van der Heyden, M 2024, 'Development of new Kir2.1 channel openers from propafenone analogues', British Journal of Pharmacology. <https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17377>
Digles, D, Ingles-Prieto, A, Dvorak, V, Mocking, TAM, Goldmann, U, Garofoli, A, Homan, EJ, Di Silvio, A, Azzollini, L, Sassone, F, Fogazza, M, Bärenz, F, Pommereau, A, Zuschlag, Y, Ooms, JF, Tranberg-Jensen, J, Hansen, JS, Stanka, J, Sijben, HJ, Batoulis, H, Bender, E, Martini, R, IJzerman, AP, Sauer, DB, Heitman, LH, Manolova, V, Reinhardt, J, Ehrmann, A, Leippe, P, Ecker, GF, Huber, KVM, Licher, T, Scarabottolo, L, Wiedmer, T & Superti-Furga, G 2024, 'Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily', Frontiers in Pharmacology, vol. 15, 1401599. https://doi.org/10.3389/fphar.2024.1401599
Granulo, N, Sosnin, S, Digles, D & Ecker, GF 2024, 'The macrocycle inhibitor landscape of SLC‐transporter', Molecular Informatics, vol. 43, no. 5, e202300287. https://doi.org/10.1002/minf.202300287
Huang, J, Osthushenrich, T, MacNamara, A, Mälarstig, A, Brocchetti, S, Bradberry, S, Scarabottolo, L, Ferrada, E, Sosnin, S, Digles, D, Superti-Furga, G & Ecker, GF 2024, 'ProteoMutaMetrics: machine learning approaches for solute carrier family 6 mutation pathogenicity prediction', Rsc advances, vol. 14, no. 19, 00748, pp. 13083-13094. https://doi.org/10.1039/d4ra00748d
Ferrada, E, Wiedmer, T, Wang, WA, Frommelt, F, Steurer, B, Klimek, C, Lindinger, S, Osthushenrich, T, Garofoli, A, Brocchetti, S, Bradberry, S, Huang, J, MacNamara, A, Scarabottolo, L, Ecker, GF, Malarstig, A & Superti-Furga, G 2024, 'Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8', Journal of Molecular Biology, vol. 436, no. 2, 168383. https://doi.org/10.1016/j.jmb.2023.168383
Activities
Showing entries 151 - 155 out of 202
Classification of ABCB1 substrates using similarity based descriptors
Rita Schwaha
,
Gerhard Ecker
XXth International Symposium on Medicinal Chemistry (EFMC-ISMC 2008)
Conference,
Poster presentation
..2008 - ..2008
Classification of insulin receptor activators with self-organising maps
Daniela Digles
,
Gerhard Ecker
,
Verena Dirsch
XXth International Symposium on Medicinal Chemistry (EFMC-ISMC 2008)
Conference,
Poster presentation
..2008 - ..2008
Comparison of contenmporary feature selection algorithms: application to the classification of substrates for ABC-transporter
Andreas Janecek
,
Michael Demel
,
Gerhard Ecker
,
Wilfried Gansterer
,
Oliver Krämer
,
Eric Haaksma
,
Peter Ettmayer
17th European Symposium on Quantitative Structure-Activity Relationships & Omics Technologies and Systems Biology
Conference,
Poster presentation
..2008 - ..2008
Docking studies on hERG potassium channels - trapping of propafenone derivatives
Evgeny Timin
,
Steffen Hering
,
Andrea Schiesaro
,
Gerhard Ecker
,
Andreas Windisch
XXth International Symposium on Medicinal Chemistry (EFMC-ISMC 2008)
Conference,
Poster presentation
..2008 - ..2008
Experimental data guided ligand docking - a tool for elucidating the binding mode of benzodiazepines
Gerhard Ecker
,
Lars Richter
,
Margot Ernst
,
Erwin Sigel
,
Werner Sieghart
XXth International Symposium on Medicinal Chemistry (EFMC-ISMC 2008)
Conference,
Poster presentation
..2008 - ..2008