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Head of Group
Director of Corporate Program
His main research interests are ligand- and structure-based drug design with focus on transmembrane transport proteins, prediction of on- and off-kinetics, as well as semantic data integration.
Publications
Showing entries 1 - 5 out of 312
Li, E, Boujeddaine, N, Houtman, MJC, Maas, Sluijter, , Ecker, G, Weinzinger, A, van Ham, W & van der Heyden, M 2024, 'Development of new Kir2.1 channel openers from propafenone analogues', British Journal of Pharmacology. <https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17377>
Digles, D, Ingles-Prieto, A, Dvorak, V, Mocking, TAM, Goldmann, U, Garofoli, A, Homan, EJ, Di Silvio, A, Azzollini, L, Sassone, F, Fogazza, M, Bärenz, F, Pommereau, A, Zuschlag, Y, Ooms, JF, Tranberg-Jensen, J, Hansen, JS, Stanka, J, Sijben, HJ, Batoulis, H, Bender, E, Martini, R, IJzerman, AP, Sauer, DB, Heitman, LH, Manolova, V, Reinhardt, J, Ehrmann, A, Leippe, P, Ecker, GF, Huber, KVM, Licher, T, Scarabottolo, L, Wiedmer, T & Superti-Furga, G 2024, 'Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily', Frontiers in Pharmacology, vol. 15, 1401599. https://doi.org/10.3389/fphar.2024.1401599
Granulo, N, Sosnin, S, Digles, D & Ecker, GF 2024, 'The macrocycle inhibitor landscape of SLC‐transporter', Molecular Informatics, vol. 43, no. 5, e202300287. https://doi.org/10.1002/minf.202300287
Huang, J, Osthushenrich, T, MacNamara, A, Mälarstig, A, Brocchetti, S, Bradberry, S, Scarabottolo, L, Ferrada, E, Sosnin, S, Digles, D, Superti-Furga, G & Ecker, GF 2024, 'ProteoMutaMetrics: machine learning approaches for solute carrier family 6 mutation pathogenicity prediction', Rsc advances, vol. 14, no. 19, 00748, pp. 13083-13094. https://doi.org/10.1039/d4ra00748d
Ferrada, E, Wiedmer, T, Wang, WA, Frommelt, F, Steurer, B, Klimek, C, Lindinger, S, Osthushenrich, T, Garofoli, A, Brocchetti, S, Bradberry, S, Huang, J, MacNamara, A, Scarabottolo, L, Ecker, GF, Malarstig, A & Superti-Furga, G 2024, 'Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8', Journal of Molecular Biology, vol. 436, no. 2, 168383. https://doi.org/10.1016/j.jmb.2023.168383
Activities
Showing entries 126 - 130 out of 202
Ligand docking of propafenones into homology models of P-glycoprotein representing two different states of the catalytic cycle
Freya Klepsch
,
Thomas Stockner
,
Peter Chiba
,
Gerhard Ecker
6th Joint Meeting on Medicinal Chemistry (EFMC)
Conference,
Poster presentation
..2009 - ..2009
Ligand-based screening tools for insulin receptor activating compounds
Daniela Digles
,
Verena Dirsch
,
Gerhard Ecker
21. Wissenschaftliche Tagung der Österreichischen Pharmazeutischen Gesellschaft
Conference,
Poster presentation
..2009 - ..2009
QSAR, HQSAR and GRIND studies on a set of heterocyclic propafenone-type inhibitors of P-glycoprotein
Ishrat Jabeen
,
Wolfgang Holzer
,
Gerhard Ecker
21. Wissenschaftliche Tagung der Österreichischen Pharmazeutischen Gesellschaft
Conference,
Poster presentation
..2009 - ..2009
QSAR-guided synthesis of chalcone-like P-glycoprotein inhibitors
Gerda Brunhofer-Bolzer
,
Thomas Erker
,
Ishrat Jabeen
,
Gerhard Ecker
,
Peter Chiba
,
Zahida Parveen
Nicht angegeben
Other,
Poster presentation
..2009 - ..2009
SIBAR descriptors for classification of P-glycoprotein substrates
Rita Schwaha
,
Gerhard Ecker
6th Joint Meeting on Medicinal Chemistry (EFMC)
Conference,
Poster presentation
..2009 - ..2009