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Head of Group
Director of Corporate Program
His main research interests are ligand- and structure-based drug design with focus on transmembrane transport proteins, prediction of on- and off-kinetics, as well as semantic data integration.
Publications
Showing entries 1 - 5 out of 311
Digles, D, Ingles-Prieto, A, Dvorak, V, Mocking, TAM, Goldmann, U, Garofoli, A, Homan, EJ, Di Silvio, A, Azzollini, L, Sassone, F, Fogazza, M, Bärenz, F, Pommereau, A, Zuschlag, Y, Ooms, JF, Tranberg-Jensen, J, Hansen, JS, Stanka, J, Sijben, HJ, Batoulis, H, Bender, E, Martini, R, IJzerman, AP, Sauer, DB, Heitman, LH, Manolova, V, Reinhardt, J, Ehrmann, A, Leippe, P, Ecker, GF, Huber, KVM, Licher, T, Scarabottolo, L, Wiedmer, T & Superti-Furga, G 2024, 'Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily', Frontiers in Pharmacology, vol. 15, 1401599. https://doi.org/10.3389/fphar.2024.1401599
Granulo, N, Sosnin, S, Digles, D & Ecker, GF 2024, 'The macrocycle inhibitor landscape of SLC‐transporter', Molecular Informatics, vol. 43, no. 5, e202300287. https://doi.org/10.1002/minf.202300287
Huang, J, Osthushenrich, T, MacNamara, A, Mälarstig, A, Brocchetti, S, Bradberry, S, Scarabottolo, L, Ferrada, E, Sosnin, S, Digles, D, Superti-Furga, G & Ecker, GF 2024, 'ProteoMutaMetrics: machine learning approaches for solute carrier family 6 mutation pathogenicity prediction', Rsc advances, vol. 14, no. 19, 00748, pp. 13083-13094. https://doi.org/10.1039/d4ra00748d
Ferrada, E, Wiedmer, T, Wang, WA, Frommelt, F, Steurer, B, Klimek, C, Lindinger, S, Osthushenrich, T, Garofoli, A, Brocchetti, S, Bradberry, S, Huang, J, MacNamara, A, Scarabottolo, L, Ecker, GF, Malarstig, A & Superti-Furga, G 2024, 'Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8', Journal of Molecular Biology, vol. 436, no. 2, 168383. https://doi.org/10.1016/j.jmb.2023.168383
Helmke, P, Füzi, B & Ecker, GF 2024, 'Bioactivity descriptors for in vivo toxicity prediction: now and the future', Expert Opinion on Drug Metabolism and Toxicology, vol. 20, no. 7, pp. 541-543. https://doi.org/10.1080/17425255.2024.2334308
Activities
Showing entries 66 - 70 out of 202
Interaction Profiling of Mephedrone at the Human Serotonin and Dopamine Transporters.
Amir Seddik
,
Rene Weissensteiner
,
Barbara Zdrazil
,
Harald H. Sitte
,
Gerhard Ecker
22nd International Symposium on Medicinal Chemistry (EFMC-ISMC 2012)
Conference,
Poster presentation
..2012 - ..2012
Search for Common Pharmacophore Patterns of TRPV1 Antagonists.
Daria Tsareva
,
Gerhard Ecker
22nd International Symposium on Medicinal Chemistry (EFMC-ISMC 2012)
Conference,
Poster presentation
..2012 - ..2012
Studying Structure-Activity Relationships in a Homology Model of the Gamma-Aminobutyric Acid Transporter 1.
Andreas Jurik
,
Barbara Zdrazil
,
Harald H. Sitte
,
Stine B. Vogensen
,
Gerhard Ecker
22nd International Symposium on Medicinal Chemistry (EFMC-ISMC 2012)
Conference,
Poster presentation
..2012 - ..2012
Synthesis and Biological Evaluation.
Rita Fürst
,
Christina Nowikow
,
Agnes Berenyi
,
Gerhard Ecker
,
Walther Schmid
,
Istvan Zupko
,
Uwe Rinner
22nd International Symposium on Medicinal Chemistry (EFMC-ISMC 2012)
Conference,
Poster presentation
..2012 - ..2012
Valerenic Acid as a Model Compound for New GABAA Receptor Ligands.
Maximilian Haider
,
Gerhard Ecker
,
Steffen Hering
,
Marko Mihovilovic
22nd International Symposium on Medicinal Chemistry (EFMC-ISMC 2012)
Conference,
Poster presentation
..2012 - ..2012