Follow me on Twitter

I agree that content from Twitter will be displayed to me.

 

Head of Group
Director of Corporate Program

His main research interests are ligand- and structure-based drug design with focus on transmembrane transport proteins, prediction of on- and off-kinetics, as well as semantic data integration.

Contact Hours for Students

  • Wednesday 14:00 - 15:00
  • Room 2E405 (or online) 
  • only after appointment via E-Mail latest on Friday before
Publications

Showing entries 1 - 5 out of 311
Digles, D, Ingles-Prieto, A, Dvorak, V, Mocking, TAM, Goldmann, U, Garofoli, A, Homan, EJ, Di Silvio, A, Azzollini, L, Sassone, F, Fogazza, M, Bärenz, F, Pommereau, A, Zuschlag, Y, Ooms, JF, Tranberg-Jensen, J, Hansen, JS, Stanka, J, Sijben, HJ, Batoulis, H, Bender, E, Martini, R, IJzerman, AP, Sauer, DB, Heitman, LH, Manolova, V, Reinhardt, J, Ehrmann, A, Leippe, P, Ecker, GF, Huber, KVM, Licher, T, Scarabottolo, L, Wiedmer, T & Superti-Furga, G 2024, 'Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily', Frontiers in Pharmacology, vol. 15, 1401599. https://doi.org/10.3389/fphar.2024.1401599

Huang, J, Osthushenrich, T, MacNamara, A, Mälarstig, A, Brocchetti, S, Bradberry, S, Scarabottolo, L, Ferrada, E, Sosnin, S, Digles, D, Superti-Furga, G & Ecker, GF 2024, 'ProteoMutaMetrics: machine learning approaches for solute carrier family 6 mutation pathogenicity prediction', Rsc advances, vol. 14, no. 19, 00748, pp. 13083-13094. https://doi.org/10.1039/d4ra00748d

Ferrada, E, Wiedmer, T, Wang, WA, Frommelt, F, Steurer, B, Klimek, C, Lindinger, S, Osthushenrich, T, Garofoli, A, Brocchetti, S, Bradberry, S, Huang, J, MacNamara, A, Scarabottolo, L, Ecker, GF, Malarstig, A & Superti-Furga, G 2024, 'Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8', Journal of Molecular Biology, vol. 436, no. 2, 168383. https://doi.org/10.1016/j.jmb.2023.168383

Activities

Drug Transporters – Structure, Function, and Modulation

Gerhard Ecker
International Workshop on New Approaches in Drug Design & Development
Seminar/Workshop, Talk or oral contribution
21.3.2012 - 21.3.2012

Knowledge driven ligand design – ligand-based design meets protein structures

Gerhard Ecker
Talk or oral contribution
7.3.2012 - 7.3.2012

Combining Binary QSAR and Docking for Structure-Activity Relationships of Tiagabine Analogs.

Andreas Jurik , Regina Reicherstorfer , Barbara Zdrazil , Gerhard Ecker
19th EuroQSAR
Conference, Poster presentation
..2012 - ..2012

Combining Ensemble Docking and Consensus Scoring to Elucidate the Binding Mode of Tiagabine Analogs in hGAT-1.

Andreas Jurik , Barbara Zdrazil , Harald H. Sitte , Stine B. Vogensen , Gerhard Ecker
3rd Strasbourg Summer School on Chemoinformatics
Summer/Winter school, Poster presentation
..2012 - ..2012

Elucidating Binding Events of Tiagabine Analogs by Molecular Dynamics – Assisted Docking Studies.

Andreas Jurik , Barbara Zdrazil , Harald H. Sitte , Gerhard Ecker
5th Annual SFB35 Symposium "Transmembrane Transporters in Health and Disease"
Conference, Poster presentation
..2012 - ..2012