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Head of Group
Director of Corporate Program
His main research interests are ligand- and structure-based drug design with focus on transmembrane transport proteins, prediction of on- and off-kinetics, as well as semantic data integration.
Publications
Showing entries 186 - 190 out of 331
Windisch, A, Timin, E, Schwarz, T, Stork, D, Erker, T, Ecker, G & Hering, S 2011, 'Trapping and dissociation of propafenone derivatives in HERG channels', British Journal of Pharmacology, vol. 162, no. 7, pp. 1542-1552. https://doi.org/10.1111/j.1476-5381.2010.01159.x
Sarker, S, Weissensteiner, R, Steiner, IM, Sitte, HH, Ecker, G, Freissmuth, M & Sucic, S 2010, 'The High-Affinity Binding Site for Tricyclic Antidepressants Resides in the Outer Vestibule of the Serotonin Transporter', Molecular Pharmacology, vol. 78, no. 6, pp. 1026-1035. https://doi.org/10.1124/mol.110.067538
Klepsch, F, Stockner, T, Erker, T, Müller, M, Chiba, P & Ecker, G 2010, 'Using Structural and Mechanistic Information to Design Novel Inhibitors/Substrates of P-Glycoprotein', Current Topics in Medicinal Chemistry, vol. 10, no. 17, pp. 1769-1774. https://doi.org/10.2174/156802610792928004
Fürst, R, Nowikow, C, Berenyi, A, Ecker, GF, Schmid, W, Zupko, I & Rinner, DIU 2010, 'Synthesis and biological evaluation of novel carbocycle-containing combretastatin A-4 analogs', American Chemical Society. Abstracts of Papers (at the National Meeting), vol. 240.
Sugano, K, Kansy, M, Artursson, P, Avdeef, A, Bendels, S, Di, L, Ecker, GF, Faller, B, Fischer, H, Gerebtzoff, G, Lennernaes, H & Senner, F 2010, 'Coexistence of passive and carrier-mediated processes in drug transport', Nature Reviews. Drug Discovery, vol. 9, no. 8, pp. 597-614. https://doi.org/10.1038/nrd3187
Projects
Molecular Drug Targets
Hering, S. (Project Lead), Ecker, G. (Co-Lead), Maulide, N. (Co-Lead), Weinzinger, A. (Co-Lead) & Gonzalez Herrero, L. (Co-Lead)
1/12/10 → 31/12/22
Project: Research funding