Exploring the molecular determinants for subtype-selectivity of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogs as betaine/GABA transporter 1 (BGT1) substrate-inhibitors

Author(s)
Stefanie Kickinger, Anas Al-Khawaja, Anne Staehr Haugaard, Maria E. K. Lie, Francesco Bavo, Rebekka Loeffler, Maria Damgaard, Gerhard F. Ecker, Bente Frolund, Petrine Wellendorph
Organisation(s)
External organisation(s)
University of Copenhagen
Journal
Scientific Reports
Volume
10
No. of pages
15
ISSN
2045-2322
DOI
https://doi.org/10.1038/s41598-020-69908-w
Publication date
08-2020
Peer reviewed
Yes
Austrian Fields of Science 2012
301207 Pharmaceutical chemistry
Keywords
Portal url
https://ucrisportal.univie.ac.at/en/publications/exploring-the-molecular-determinants-for-subtypeselectivity-of-2amino1456tetrahydropyrimidine5carboxylic-acid-analogs-as-betainegaba-transporter-1-bgt1-substrateinhibitors(cb73ce37-7d25-44f5-b465-d074e114b463).html