Open PHACTS: semantic interoperability for drug discovery.

Author(s)
Antony J. Williams, Lee Harland, Paul Groth, Stephen Pettifer, Christine Chichester, Egon L. Willighagen, Chris T. Evelo, Niklas Blomberg, Gerhard Ecker, Carole Goble, Barend Mons
Abstract

Open PHACTS is a public-private partnership between academia, publishers, small and medium sized enterprises and pharmaceutical companies. The goal of the project is to deliver and sustain an 'open pharmacological space' using and enhancing state-of-the-art semantic web standards and technologies. It is focused on practical and robust applications to solve specific questions in drug discovery research. OPS is intended to facilitate improvements in drug discovery in academia and industry and to support open innovation and in-house non-public drug discovery research. This paper lays out the challenges and how the Open PHACTS project is hoping to address these challenges technically and socially.

Organisation(s)
External organisation(s)
Royal Society of Chemistry, Connected Discovery Ltd, Vrije Universiteit Amsterdam, University of Manchester, Swiss Institute of Bioinformatics, Maastricht University (UM), Netherlands Bioinformatics Center, AstraZeneca, Leiden University
Journal
Drug Discovery Today
Volume
17
Pages
1188-1198
No. of pages
11
ISSN
1359-6446
DOI
https://doi.org/10.1016/j.drudis.2012.05.016
Publication date
2012
Peer reviewed
Yes
Austrian Fields of Science 2012
301207 Pharmaceutical chemistry, 301305 Medical chemistry
Portal url
https://ucrisportal.univie.ac.at/en/publications/b0cb0d19-5dbb-481c-8c3a-4ef2de25cbda