The ABC of Phytohormone Translocation

Author(s)
Eva Hellsberg, Floriane Montanari, Gerhard F Ecker
Abstract

ATP-driven transport across biological membranes is a key process to translocate solutes from the interior of the cell to the extracellular environment. In humans, ATP-binding cassette transporters are involved in absorption, distribution, metabolism, excretion, and toxicity, and also play a major role in anticancer drug resistance. Analogous transporters are also known to be involved in phytohormone translocation. These include, e.g., the transport of auxin by ABCB1/19 in Arabidopsis thaliana, the transport of abscisic acid by AtABCG25, and the transport of strigolactone by the Petunia hybrida ABC transporter PDR1. Within this article, we outline the current knowledge about plant ABC transporters with respect to their structure and function, and provide, for the first time, a protein homology model of the strigolactone transporter PDR1 from P. hybrida.

Organisation(s)
Journal
Planta Medica: natural products and medicinal plant research
Volume
81
Pages
474-487
No. of pages
14
ISSN
0032-0943
DOI
https://doi.org/10.1055/s-0035-1545880
Publication date
04-2015
Peer reviewed
Yes
Austrian Fields of Science 2012
301204 Pharmacognosy
Keywords
ASJC Scopus subject areas
Drug Discovery, Analytical Chemistry, Molecular Medicine, Complementary and alternative medicine, Pharmacology, Pharmaceutical Science, Organic Chemistry
Portal url
https://ucrisportal.univie.ac.at/en/publications/7610d389-6fdd-41cc-8e5f-ad1060374836