Translation Termination Factor GSPT1 Is a Phenotypically Relevant Off-Target of Heterobifunctional Phthalimide Degraders

Author(s)
Mette Ishoey, Someth Chorn, Natesh Singh, Martin G Jaeger, Matthias Brand, Joshiawa Paulk, Sophie Bauer, Michael A Erb, Katja Parapatics, André C Müller, Keiryn L Bennett, Gerhard F Ecker, James E Bradner, Georg E Winter
Organisation(s)
Department of Occupational, Economic and Social Psychology
External organisation(s)
Dana-Farber Cancer Institute, Österreichische Akademie der Wissenschaften (ÖAW), Novartis Institutes for BioMedical Research
Journal
ACS Chemical Biology
Volume
13
Pages
553-560
No. of pages
8
ISSN
1554-8929
DOI
https://doi.org/10.1021/acschembio.7b00969
Publication date
03-2018
Peer reviewed
Yes
Austrian Fields of Science 2012
106001 General biology
Keywords
ASJC Scopus subject areas
Molecular Medicine, Biochemistry
Portal url
https://ucrisportal.univie.ac.at/en/publications/translation-termination-factor-gspt1-is-a-phenotypically-relevant-offtarget-of-heterobifunctional-phthalimide-degraders(3f5c787e-5ec6-4cf1-b048-82c7727dbd83).html