Passive Lipoidal Diffusion and Carrier-Mediated Cell Uptake Are Both Important Mechanisms of Membrane Permeation in Drug Disposition

Author(s)
Dennis Smith, Per Artursson, Alex Avdeef, Li Di, Gerhard F. Ecker, Bernard Faller, J. Brian Houston, Manfred Kansy, Edward H. Kerns, Stefanie D. Kramer, Hans Lennernaes, Han van de Waterbeemd, Kiyohiko Sugano, Bernard Testa
Organisation(s)
External organisation(s)
Eidgenössische Technische Hochschule Zürich, Uppsala University, Emerging Science & Innovation, Novartis Institute for Biomedical Research, University of Manchester, F. Hoffmann-La Roche AG, National Institutes of Health (NIH), Pfizer Ltd, Université de Lausanne, Independent researcher, Independent researcher, Independent researcher
Journal
Molecular Pharmaceutics
Volume
11
Pages
1727-1738
No. of pages
12
ISSN
1543-8384
DOI
https://doi.org/10.1021/mp400713v
Publication date
06-2014
Peer reviewed
Yes
Austrian Fields of Science 2012
301207 Pharmaceutical chemistry
Keywords
Portal url
https://ucrisportal.univie.ac.at/en/publications/384cf435-3506-49d1-9b87-1f5d86579a57