Currently on maternity leave.

Postdoc

Daniela Digles is senior lecturer at the Department of Pharmaceutical Sciences, University of Vienna. She completed her PhD studies with a DOC-fFORTE-fellowship of the Austrian Academy of Sciences at the University of Vienna, in the Pharmacoinformatics Research Group of Prof. Gerhard Ecker.

In 2012 she started her Post-doc within the Open PHACTS project (IMI), and later on within the Open PHACTS Foundation, where she was testing the developed system, creating KNIME workflows to access the data to answer research questions, as well as user support. Next, she was involved in the FAIRness for Life Science Data in Austria project as well as the RESOLUTE project (IMI). Furthermore, she is a community curator of WikiPathways.

Her main research interests are the usage and quality control of open data (especially for solute carrier proteins), classification schemes, and the application of KNIME to connect data resources.

Publications

Showing entries 1 - 5 out of 21
Digles, D, Ingles-Prieto, A, Dvorak, V, Mocking, TAM, Goldmann, U, Garofoli, A, Homan, EJ, Di Silvio, A, Azzollini, L, Sassone, F, Fogazza, M, Bärenz, F, Pommereau, A, Zuschlag, Y, Ooms, JF, Tranberg-Jensen, J, Hansen, JS, Stanka, J, Sijben, HJ, Batoulis, H, Bender, E, Martini, R, IJzerman, AP, Sauer, DB, Heitman, LH, Manolova, V, Reinhardt, J, Ehrmann, A, Leippe, P, Ecker, GF, Huber, KVM, Licher, T, Scarabottolo, L, Wiedmer, T & Superti-Furga, G 2024, 'Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily', Frontiers in Pharmacology, vol. 15, 1401599. https://doi.org/10.3389/fphar.2024.1401599

Huang, J, Osthushenrich, T, MacNamara, A, Mälarstig, A, Brocchetti, S, Bradberry, S, Scarabottolo, L, Ferrada, E, Sosnin, S, Digles, D, Superti-Furga, G & Ecker, GF 2024, 'ProteoMutaMetrics: machine learning approaches for solute carrier family 6 mutation pathogenicity prediction', Rsc advances, vol. 14, no. 19, 00748, pp. 13083-13094. https://doi.org/10.1039/d4ra00748d

Agrawal, A, Balcı, H, Hanspers, K, Coort, SL, Martens, M, Slenter, DN, Ehrhart, F, Digles, D, Waagmeester, A, Wassink, I, Abbassi-Daloii, T, Lopes, EN, Iyer, A, Acosta, JM, Willighagen, LG, Nishida, K, Riutta, A, Basaric, H, Evelo, CT, Willighagen, EL, Kutmon, M & Pico, AR 2024, 'WikiPathways 2024: next generation pathway database', Nucleic Acids Research, vol. 52, no. D1, pp. D679-D689. https://doi.org/10.1093/nar/gkad960

Hanspers, K, Kutmon, M, Coort, SL, Digles, D, Dupuis, LJ, Ehrhart, F, Hu, F, Lopes, EN, Martens, M, Pham, N, Shin, W, Slenter, DN, Waagmeester, A, Willighagen, EL, Winckers, LA, Evelo, CT & Pico, AR 2021, 'Ten simple rules for creating reusable pathway models for computational analysis and visualization', PLoS Computational Biology, vol. 17, no. 8, e1009226. https://doi.org/10.1371/journal.pcbi.1009226

Activities

Showing entries 6 - 10 out of 21

Triangulation of repurposing candidates for orphan diseases

Jana Gurinova , Gerhard Ecker , Daniela Digles
Nicht angegeben
Other, Poster presentation
19.3.2018 - 19.3.2018

KNIME + Open PHACTS & Hands-on

Daniela Digles
BioExcel: workflow training for computational biomolecular research
Seminar/Workshop, Talk or oral contribution
20.10.2016 - 20.10.2016

Drug Targets in the Solute Carrier Classification (SLC)

Daniela Digles
XXIV EFMC International Symposium on Medicinal Chemistry
Conference, Talk or oral contribution
31.8.2016 - 31.8.2016

Exploring available compound data with the open PHACTS discovery platform and KNIME

Daniela Digles
252nd ACS National Meeting
Conference, Talk or oral contribution
21.8.2016 - 21.8.2016

Academic use case: ErbB signaling

Daniela Digles
“Open PHACTS for Academia” – Community Workshop
Seminar/Workshop, Talk or oral contribution
26.6.2014 - 26.6.2014