Dipl.-Ing. (FH) Dr. Daniela Digles
T: +43-1-4277-55007
Hanspers, K, Kutmon, M, Coort, SL, Digles, D, Dupuis, LJ, Ehrhart, F, Hu, F, Lopes, EN, Martens, M, Pham, N, Shin, W, Slenter, DN, Waagmeester, A, Willighagen, EL, Winckers, LA, Evelo, CT & Pico, AR 2021, 'Ten simple rules for creating reusable pathway models for computational analysis and visualization', PLoS Computational Biology, vol. 17, no. 8, e1009226. https://doi.org/10.1371/journal.pcbi.1009226

Dvorak, V, Wiedmer, T, Ingles-Prieto, A, Altermatt, P, Batoulis, H, Bärenz, F, Bender, E, Digles, D, Dürrenberger, F, Heitman, LH, IJzerman, AP, Kell, DB, Kickinger, S, Körzö, D, Leippe, P, Licher, T, Manolova, V, Rizzetto, R, Sassone, F, Scarabottolo, L, Schlessinger, A, Schneider, V, Sijben, HJ, Steck, A-L, Sundström, H, Tremolada, S, Wilhelm, M, Wright Muelas, M, Zindel, D, Steppan, CM & Superti-Furga, G 2021, 'An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters', Frontiers in Pharmacology, vol. 12, 722889. https://doi.org/10.3389/fphar.2021.722889

Martens, M, Ammar, A, Riutta, A, Waagmeester, A, Slenter, DN, Hanspers, K, Miller, R, Digles, D, Lopes, E, Ehrhart, F, Dupuis, L, Winckers, L, Coort, SL, Willighagen, EL, Evelo, CT, Pico, AR & Kutmon, M 2021, 'WikiPathways: Connecting Communities', Nucleic Acids Research, vol. 49, no. D1, pp. D613–D621. https://doi.org/10.1093/nar/gkaa1024

Superti-Furga, G, Lackner, D, Wiedmer, T, Ingles-Prieto, A, RESOLUTE consortium & Steppan, C 2020, 'The RESOLUTE consortium: unlocking SLC transporters for drug discovery', Nature Reviews. Drug Discovery, vol. 19, no. 7, pp. 429-430. https://doi.org/10.1038/d41573-020-00056-6




Digles, D, Caracoti, A & Jacoby, E 2018, Accessing the Open PHACTS Discovery Platform with Workflow Tools. in B Wagner (ed.), Phenotypic Screening: Methods and Protocols. Springer, New York, Methods in Molecular Biology, vol. 1787, pp. 183-193. https://doi.org/10.1007/978-1-4939-7847-2_14

Kotsampasakou, E, Jain, S, Digles, D & Ecker, GF 2018, Transporters in Hepatotoxicity. in Computational Toxicology: Risk Assessment for Chemicals. Wiley, pp. 145-174. https://doi.org/10.1002/9781119282594.ch6

Slenter, DN, Kutmon, M, Hanspers, K, Riutta, A, Windsor, J, Nunes, N, Mélius, J, Cirillo, E, Coort, SL, Digles, D, Ehrhart, F, Giesbertz, P, Kalafati, M, Martens, M, Miller, R, Nishida, K, Rieswijk, L, Waagmeester, A, Eijssen, LMT, Evelo, CT, Pico, AR & Willighagen, EL 2018, 'WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research', Nucleic Acids Research, vol. 46, no. D1, pp. D661–D667. https://doi.org/10.1093/nar/gkx1064


Viereck, M, Gaulton, A & Digles, D 2017, Insights into Transporter Classifications: an Outline of Transporters as Drug Targets. in Transporters as Drug Targets. Wiley-VCH Verlag, pp. 1-20. https://doi.org/10.1002/9783527679430.ch1


Digles, D, Zdrazil, B, Neefs, JM, Van Vlijmen, H, Herhaus, C, Caracoti, A, Brea, J, Roibás, B, Loza, MI, Queralt-Rosinach, N, Furlong, LI, Gaulton, A, Bartek, L, Senger, S, Chichester, C, Engkvist, O, Evelo, CT, Franklin, NI, Marren, D, Ecker, GF & Jacoby, E 2016, 'Open PHACTS computational protocols for in silico target validation of cellular phenotypic screens: Knowing the knowns', MedChemComm, vol. 7, no. 6, pp. 1237-1244. https://doi.org/10.1039/c6md00065g


Ratnam, J, Zdrazil, B, Digles, D, Cuadrado-Rodriguez, E, Neefs, J-M, Tipney, H, Siebes, R, Waagmeester, A, Bradley, G, Chau, CH, Richter, L, Brea, J, Evelo, CT, Jacoby, E, Senger, S, Loza, MI, Ecker, GF & Chichester, C 2014, 'The Application of the Open Pharmacological Concepts Triple Store (Open PHACTS) to Support Drug Discovery Research', PLoS ONE, vol. 9, no. 12, e115460. https://doi.org/10.1371/journal.pone.0115460



Batchelor, C, Brenninkmeijer, CYA, Chichester, C, Davies, M, Digles, D, Dunlop, I, Evelo, CT, Gaulton, A, Goble, C, Gray, AJG, Groth, P, Harland, L, Karapetyan, K, Loizou, A, Overington, JP, Pettifer, S, Steele, J, Stevens, R, Tkachenko, V, Waagmeester, A, Williams, A & Willighagen, EL 2014, Scientific lenses to support multiple views over linked chemistry data. in Lecture Notes in Computer Science: The Semantic Web – ISWC 2014. vol. 8796, Springer, Lecture Notes in Computer Science, vol. 8796, pp. 98-113, 13th International Semantic Web Conference, ISWC 2014, Riva del Garda, Italy, 19/10/14. https://doi.org/10.1007/978-3-319-11964-9_7


Accessing public databases with KNIME

Daniela Digles (Speaker)

17 Sep 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


ReSOLUTE databases and tools for the scientific community

Daniela Digles (Speaker)

20 Sep 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


KNIME + Open PHACTS & Hands-on

Daniela Digles (Speaker)

20 Oct 2016

Activity: Talks and presentationsTalk or oral contributionOther


Drug Targets in the Solute Carrier Classification (SLC)

Daniela Digles (Speaker)

31 Aug 2016

Activity: Talks and presentationsTalk or oral contributionOther


Exploring available compound data with the open PHACTS discovery platform and KNIME

Daniela Digles (Speaker)

21 Aug 2016

Activity: Talks and presentationsTalk or oral contributionOther


Academic use case: ErbB signaling

Daniela Digles (Speaker)

26 Jun 2014

Activity: Talks and presentationsTalk or oral contributionOther


Using the Open PHACTS API with KNIME

Daniela Digles (Speaker)

26 Jun 2014

Activity: Talks and presentationsTalk or oral contributionOther


Knowledge management for transmembrane transporters

Daniela Digles (Speaker)

30 Oct 2013

Activity: Talks and presentationsTalk or oral contributionOther


In silico screening for insulin mimetic compounds using self-organizing maps

Daniela Digles (Speaker)

19 Apr 2012

Activity: Talks and presentationsTalk or oral contributionOther


Department of Pharmaceutical Sciences

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Room: 2E407

T: +43-1-4277-55007

daniela.digles@univie.ac.at