Publications, Patents, Books and Book Chapters
Showing entries 81 - 90 out of 284
2018
Siebert, DCB, Wieder, M, Schlener, L, Scholze, P, Boresch, S, Langer, T, Schnürch, M, Mihovilovic, MD, Richter, L, Ernst, M & Ecker, G 2018, 'SAR-Guided Scoring Function and Mutational Validation Reveal the Binding Mode of CGS-8216 at the α1+/γ2- Benzodiazepine Site', Journal of Chemical Information and Modeling, vol. 58, no. 8, pp. 1682-1696. https://doi.org/10.1021/acs.jcim.8b00199
Digles, D, Dangl, A, Senger, S & Ecker, G 2018, 'Open PHACTS – Semantische Datenintegration für die pharmazeutische Forschung: Open PHACTS – Semantic data integration for pharmaceutical research ', Pharmakon, vol. 6, no. 4, pp. 268-275. https://doi.org/10.1691/pn.20180026
Schuetz, DA, Richter, L, Amaral, M, Grandits, M, Graedler, U, Musil, D, Buchstaller, H-P, Eggenweiler, H-M, Frech, M & Ecker, GF 2018, 'Ligand Desolvation steers on-rate and impacts Drug Residence Time of Heat shock protein 90 (Hsp90) Inhibitors', Journal of Medicinal Chemistry, vol. 61, no. 10, pp. 4397–4411. https://doi.org/10.1021/acs.jmedchem.8b00080
Digles, D, Caracoti, A & Jacoby, E 2018, Accessing the Open PHACTS Discovery Platform with Workflow Tools. in B Wagner (ed.), Phenotypic Screening: Methods and Protocols. Springer, New York, Methods in Molecular Biology, vol. 1787, pp. 183-193. https://doi.org/10.1007/978-1-4939-7847-2_14
Estrada-Tejedor, R & Ecker, GF 2018, 'Predicting drug resistance related to ABC transporters using unsupervised Consensus Self-Organizing Maps', Scientific Reports, vol. 8, no. 1, 6803. https://doi.org/10.1038/s41598-018-25235-9
Jain, S, Kotsampasakou, E & Ecker, GF 2018, 'Comparing the performance of meta-classifiers-a case study on selected imbalanced data sets relevant for prediction of liver toxicity', Journal of Computer-Aided Molecular Design, vol. 32, no. 5, pp. 583-590. https://doi.org/10.1007/s10822-018-0116-z
Singh, N & Ecker, GF 2018, 'Insights into the Structure, Function, and Ligand Discovery of the Large Neutral Amino Acid Transporter 1, LAT1', International Journal of Molecular Sciences, vol. 19, no. 5, 1278. https://doi.org/10.3390/ijms19051278
Ishoey, M, Chorn, S, Singh, N, Jaeger, MG, Brand, M, Paulk, J, Bauer, S, Erb, MA, Parapatics, K, Müller, AC, Bennett, KL, Ecker, GF, Bradner, JE & Winter, GE 2018, 'Translation Termination Factor GSPT1 Is a Phenotypically Relevant Off-Target of Heterobifunctional Phthalimide Degraders', ACS Chemical Biology, vol. 13, no. 3, pp. 553-560. https://doi.org/10.1021/acschembio.7b00969
Kotsampasakou, E, Jain, S, Digles, D & Ecker, GF 2018, Transporters in Hepatotoxicity. in Computational Toxicology: Risk Assessment for Chemicals. Wiley, pp. 145-174. https://doi.org/10.1002/9781119282594.ch6
Slenter, DN, Kutmon, M, Hanspers, K, Riutta, A, Windsor, J, Nunes, N, Mélius, J, Cirillo, E, Coort, SL, Digles, D, Ehrhart, F, Giesbertz, P, Kalafati, M, Martens, M, Miller, R, Nishida, K, Rieswijk, L, Waagmeester, A, Eijssen, LMT, Evelo, CT, Pico, AR & Willighagen, EL 2018, 'WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research', Nucleic Acids Research, vol. 46, no. D1, pp. D661–D667. https://doi.org/10.1093/nar/gkx1064
Showing entries 81 - 90 out of 284