Publications, Patents, Books and Book Chapters


2018


Kotsampasakou, E, Jain, S, Digles, D & Ecker, GF 2018, Transporters in Hepatotoxicity. in Computational Toxicology: Risk Assessment for Chemicals. Wiley, pp. 145-174. doi.org/10.1002/9781119282594.ch6


Slenter, DN, Kutmon, M, Hanspers, K, Riutta, A, Windsor, J, Nunes, N, Mélius, J, Cirillo, E, Coort, SL, Digles, D, Ehrhart, F, Giesbertz, P, Kalafati, M, Martens, M, Miller, R, Nishida, K, Rieswijk, L, Waagmeester, A, Eijssen, LMT, Evelo, CT, Pico, AR & Willighagen, EL 2018, 'WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research', Nucleic Acids Research, vol. 46, no. D1, pp. D661–D667. doi.org/10.1093/nar/gkx1064


2017


Sanz, F, Pognan, F, Steger-Hartmann, T, Díaz, C, Cases, M, Pastor, M, Marc, P, Wichard, J, Briggs, K, Watson, DK, Kleinöder, T, Yang, C, Amberg, A, Beaumont, M, Brookes, AJ, Brunak, S, Cronin, MTD, Ecker, GF, Escher, S, Greene, N, Guzmán, A, Hersey, A, Jacques, P, Lammens, L, Mestres, J, Muster, W, Northeved, H, Pinches, M, Saiz, J, Sajot, N, Valencia, A, van der Lei, J, Vermeulen, NPE, Vock, E, Wolber, G & Zamora, I 2017, 'Legacy data sharing to improve drug safety assessment: the eTOX project', Nature Reviews. Drug Discovery, vol. 16, no. 12, pp. 811-812. doi.org/10.1038/nrd.2017.177


Jorgensen, L, Al-Khawaja, A, Kickinger, S, Vogensen, SB, Skovgaard-Petersen, J, Rosenthal, E, Borkar, N, Loffler, R, Madsen, KK, Brauner-Osbome, H, Schousboe, A, Ecker, GF, Wellendorph, P & Causen, RP 2017, 'Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1)', Journal of Medicinal Chemistry, vol. 60, no. 21, pp. 8834-8846. doi.org/10.1021/acs.jmedchem.7b00924


Leist, M, Ghallab, A, Graepel, R, Marchan, R, Hassan, R, Bennekou, SH, Limonciel, A, Vinken, M, Schildknecht, S, Waldmann, T, Danen, E, van Ravenzwaay, B, Kamp, H, Gardner, I, Godoy, P, Bois, FY, Braeuning, A, Reif, R, Oesch, F, Drasdo, D, Höhme, S, Schwarz, M, Hartung, T, Braunbeck, T, Beltman, J, Vrieling, H, Sanz, F, Forsby, A, Gadaleta, D, Fisher, C, Kelm, J, Fluri, D, Ecker, G, Zdrazil, B, Terron, A, Jennings, P, van der Burg, B, Dooley, S, Meijer, AH, Willighagen, E, Martens, M, Evelo, C, Mombelli, E, Taboureau, O, Mantovani, A, Hardy, B, Koch, B, Escher, S, van Thriel, C, Cadenas, C, Kroese, D, van de Water, B & Hengstler, JG 2017, 'Adverse outcome pathways: opportunities, limitations and open questions', Archives of Toxicology, vol. 91, no. 11, pp. 3477–3505. doi.org/10.1007/s00204-017-2045-3


Damgaard, M, Haugaard, AS, Kickinger, S, Al-Khawaja, A, Lie, MEK, Ecker, G, Clausen, RP & Frølund, B 2017, Development of Non-GAT1-Selective Inhibitors: Challenges and Achievements. in A Ortega & A Schousboe (eds), Glial Amino Acid Transporters. Springer, Advances in Neurobiology.


Schuetz, DA, de Witte, WEA, Wong, YC, Knasmueller, B, Richter, L, Kokh, DB, Sadiq, SK, Bosma, R, Nederpelt, I, Heitman, LH, Segala, E, Amaral, M, Guo, D, Andres, D, Georgi, V, Stoddart, LA, Hill, S, Cooke, RM, De Graaf, C, Leurs, R, Frech, M, Wade, RC, de Lange, ECM, IJzerman, AP, Müller-Fahrnow, A & Ecker, GF 2017, 'Kinetics for Drug Discovery: an industry-driven effort to target drug residence time', Drug Discovery Today, vol. 22, no. 6, pp. 896-911. doi.org/10.1016/j.drudis.2017.02.002