Publications, Patents, Books and Book Chapters
Showing entries 31 - 40 out of 259
2021
Van der Stel, W, Carta, G, Eakins, J, Delp, J, Suciu, I, Forsby, A, Cediel-Ulloa, A, Attoff, K, Troger, F, Kamp, H, Gardner, I, Zdrazil, B, Moné, MJ, Ecker, GF, Pastor, M, Gómez-Tamayo, JC, White, A, Danen, EHJ, Leist, M, Walker, P, Jennings, P, Hougaard Bennekou, S & Van de Water, B 2021, 'New approach methods supporting read-across: Two neurotoxicity AOP-based IATA case studies', Altex, vol. 38, no. 4, pp. 615-635. https://doi.org/10.14573/altex.2103051
Füzi, B, Gurinova, J, Hermjakob, H, Ecker, G & Malik-Sheriff, RS 2021, 'Path4Drug: Data Science Workflow for Identification of Tissue-Specific Biological Pathways Modulated by Toxic Drugs', Frontiers in Pharmacology, vol. 12, 708296. https://doi.org/10.3389/fphar.2021.708296
2020
Cosco, J, Scalise, M, Colas, C, Galluccio, M, Martini, R, Rovella, F, Mazza, T, Ecker, GF & Indiveri, C 2020, 'ATP modulates SLC7A5 (LAT1) synergistically with cholesterol', Scientific Reports, vol. 10, no. 1, 16738, pp. 16738. https://doi.org/10.1038/s41598-020-73757-y
Kickinger, S, Al-Khawaja, A, Haugaard, AS, Lie, MEK, Bavo, F, Loeffler, R, Damgaard, M, Ecker, GF, Frolund, B & Wellendorph, P 2020, 'Exploring the molecular determinants for subtype-selectivity of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogs as betaine/GABA transporter 1 (BGT1) substrate-inhibitors', Scientific Reports, vol. 10, no. 1, 12992. https://doi.org/10.1038/s41598-020-69908-w
Hemmerich, J & Ecker, GF 2020, 'In silico toxicology: From structure–activity relationships towards deep learning and adverse outcome pathways', Wiley Interdisciplinary Reviews. Computational Molecular Science, vol. 10, no. 4, e1475. https://doi.org/10.1002/wcms.1475
Troger, F, Delp, J, Funke, M, van der Stel, W, Colas, C, Leist, M, van de Water, B & Ecker, GF 2020, 'Identification of mitochondrial toxicants by combined in silico and in vitro studies – A structure-based view on the adverse outcome pathway', Computational Toxicology, vol. 14, 100123, pp. 100123. https://doi.org/10.1016/j.comtox.2020.100123
Hemmerich, J, Troger, F, Fuezi, B & Ecker, GF 2020, 'Using Machine Learning Methods and Structural Alerts for Prediction of Mitochondrial Toxicity', Molecular Informatics, vol. 39, no. 5, 2000005. https://doi.org/10.1002/minf.202000005
Colas, C, Banci, G, Martini, R & Ecker, G 2020, 'Studies of structural determinants of substrate binding in the Creatine Transporter (CreaT, SLC6A8) using molecular models', Scientific Reports, vol. 10, no. 1, 6241. https://doi.org/10.1038/s41598-020-63189-z
Superti-Furga, G, Lackner, D, Wiedmer, T, Ingles-Prieto, A, RESOLUTE consortium & Steppan, C 2020, 'The RESOLUTE consortium: unlocking SLC transporters for drug discovery', Nature Reviews. Drug Discovery, vol. 19, no. 7, pp. 429-430. https://doi.org/10.1038/d41573-020-00056-6
Lie, MEK, Kickinger, S, Skovgaard-Petersen, J, Ecker, GF, Clausen, RP, Schousboe, A, White, HS & Wellendorph, P 2020, 'Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects', Neurochemical research, vol. 45, 1551–1565, pp. 1551-1565. https://doi.org/10.1007/s11064-020-03017-y
Showing entries 31 - 40 out of 259