The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds

Author(s)
Tim Brecklinghaus, Wiebke Albrecht, Franziska Kappenberg, Julia Duda, Nachiket Vartak, Karolina Edlund, Rosemarie Marchan, Ahmed Ghallab, Cristina Cadenas, Georgia Günther, Marcel Leist, Mian Zhang, Iain Gardner, Jörg Reinders, Frans GM Russel, Alison J. Foster, Dominic P. Williams, Amruta Damle-Vartak, Melanie Grandits, Gerhard Ecker, Naim Kittana, Jörg Rahnenführer, Jan G. Hengstler
Organisation(s)
Department of Pharmaceutical Sciences
External organisation(s)
Leibniz-Institut für Arbeitsforschung an der TU Dortmund, Technische Universität Dortmund, South Valley University, Universität Konstanz, Simcyp (a Certara company), Radboud University, AstraZeneca, Stiftung Deutsches Krebsforschungszentrum, An-Najah National University
Journal
Chemico-Biological Interactions
Volume
351
No. of pages
16
ISSN
0009-2797
DOI
https://doi.org/10.1016/j.cbi.2021.109728
Publication date
01-2022
Peer reviewed
Yes
Austrian Fields of Science 2012
301207 Pharmaceutical chemistry
Keywords
ASJC Scopus subject areas
Toxicology
Portal url
https://ucrisportal.univie.ac.at/en/publications/the-hepatocyte-export-carrier-inhibition-assay-improves-the-separation-of-hepatotoxic-from-nonhepatotoxic-compounds(1705e071-3914-4f72-a799-290ff2dfc424).html