Senior scientist

Melanie Grandits is senior scientist at the Division of Pharmaceutical Chemistry at the University of Vienna. She is a biotechnologist by training and did her PhD studies in Computational Biology in the field of molecular dynamics simulations. She started her Postdoctoral Research within the K4DD project, where she investigated the kinetics of compounds with the human P-glycoprotein. At the moment she is involved in the eTransafe project, building classification models of transport proteins using machine learning approaches.


Showing entries 6 - 10 out of 11
Superti-Furga G, Lackner D, Wiedmer T, Ingles-Prieto A, RESOLUTE consortium, Steppan C. The RESOLUTE consortium: unlocking SLC transporters for drug discovery. Nature Reviews. Drug Discovery. 2020 Apr 7;19(7):429-430. doi: 10.1038/d41573-020-00056-6

Schuetz DA, Richter L, Amaral M, Grandits M, Graedler U, Musil D et al. Ligand Desolvation steers on-rate and impacts Drug Residence Time of Heat shock protein 90 (Hsp90) Inhibitors. Journal of Medicinal Chemistry. 2018 May 24;61(10):4397–4411. doi: 10.1021/acs.jmedchem.8b00080