News Archive

Publication
 

Chemical compound bioactivity and related data are nowadays easily available from open data sources and the open medicinal chemistry literature for...

Publication
 

Hyperbilirubinemia is a pathological condition of excessive accumulation of conjugated or unconjugated bilirubin in blood. It has been associated with...

News
 

TransQST - We will be working on this new project funded by the Innovative Medicine Initiative (IMI2) starting in 2017. It's an european collaborative...

Publication
 

With the public availability of large data sources such as ChEMBLdb and the Open PHACTS Discovery Platform, retrieval of data sets for certain protein...

News
 

Dr. Barbara Zdrazil recently received funding for a new FWF stand-alone project "Elucidating hepatic OATP-ligand interactions and selectivity" (P...

Publication
 

The breast cancer resistance protein (BCRP) is an ABC transporter playing a crucial role in the pharmacokinetics of drugs. The early identification of...

Publication
 

Retrieval of congeneric and consistent SAR data sets for protein targets of interest is still a laborious task to do if no appropriate in-house data...

Publication
 

Phenotypic screening is in a renaissance phase and is expected by many academic and industry leaders to accelerate the discovery of new drugs for new...

News
 

Die Suche nach neuen Medikamenten ist ein kostspieliges, langwieriges Unterfangen. Mit Open PHACTS gibt es nun eine innovative Plattform, die von...

Forschungsnewsletter April 2016
Publication
 

The transmembrane ABC transporters P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) are widely recognized for their role in cancer...

Publication
 

The human ATP binding cassette transporters Breast Cancer Resistance Protein (BCRP) and Multidrug Resistance Protein 1 (P-gp) are co-expressed in many...

Book Chapter
 

Computational Chemogenomics, Pan Stanford Publishing

ISBN: 9789814411394

This book focuses on applications of compound library design and virtual...