Dipl.-Ing. (FH) Dr. Daniela Digles
T: +43-1-4277-55007
Summer term 2018
Winter term 2017
Summer term 2017
321024 PR Arzneistoffanalytik - B12 - (5 Kurse)
Slenter, DN, Kutmon, M, Hanspers, K, Riutta, A, Windsor, J, Nunes, N, Mélius, J, Cirillo, E, Coort, SL, Digles, D, Ehrhart, F, Giesbertz, P, Kalafati, M, Martens, M, Miller, R, Nishida, K, Rieswijk, L, Waagmeester, A, Eijssen, LMT, Evelo, CT, Pico, AR & Willighagen, EL 2018, 'WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research' Nucleic Acids Research, Bd 46, Nr. D1, S. D661–D667. DOI: 10.1093/nar/gkx1064
Goldmann, D, Zdrazil, B, Digles, D & Ecker, GF 2017, 'Empowering pharmacoinformatics by linked life science data' Journal of Computer-Aided Molecular Design, Bd 31, Nr. 3, S. 319-328. DOI: 10.1007/s10822-016-9990-4
Viereck, M, Gaulton, A & Digles, D 2017, Insights into Transporter Classifications: an Outline of Transporters as Drug Targets. in Transporters as Drug Targets. Wiley-VCH Verlag, S. 1-20. DOI: 10.1002/9783527679430.ch1
Montanari, F, Zdrazil, B, Digles, D & Ecker, GF 2016, 'Selectivity profiling of BCRP versus P-gp inhibition: from automated collection of polypharmacology data to multi-label learning' Journal of Cheminformatics, Bd 8, S. 7. DOI: 10.1186/s13321-016-0121-y
Digles, D, Zdrazil, B, Neefs, JM, Van Vlijmen, H, Herhaus, C, Caracoti, A, Brea, J, Roibás, B, Loza, MI, Queralt-Rosinach, N, Furlong, LI, Gaulton, A, Bartek, L, Senger, S, Chichester, C, Engkvist, O, Evelo, CT, Franklin, NI, Marren, D, Ecker, GF & Jacoby, E 2016, 'Open PHACTS computational protocols for in silico target validation of cellular phenotypic screens: Knowing the knowns' MedChemComm, Bd 7, Nr. 6, S. 1237-1244. DOI: 10.1039/c6md00065g
Chichester, C, Digles, D, Siebes, R, Loizou, A, Groth, P & Harland, L 2015, 'Drug discovery FAQs: Workflows for answering multidomain drug discovery questions' Drug Discovery Today, Bd 20, Nr. 4, S. 399-405. DOI: 10.1016/j.drudis.2014.11.006
Ratnam, J, Zdrazil, B, Digles, D, Cuadrado-Rodriguez, E, Neefs, J-M, Tipney, H, Siebes, R, Waagmeester, A, Bradley, G, Chau, CH, Richter, L, Brea, J, Evelo, CT, Jacoby, E, Senger, S, Loza, MI, Ecker, GF & Chichester, C 2014, 'The Application of the Open Pharmacological Concepts Triple Store (Open PHACTS) to Support Drug Discovery Research' PLOS ONE, Bd 9, Nr. 12, S. e115460. DOI: 10.1371/journal.pone.0115460
Viereck, M, Gaulton, A, Digles, D & Ecker, GF 2014, 'Transporter taxonomy - a comparison of different transport protein classification schemes' Drug Discovery Today: Technologies, Bd 12, S. e37-46. DOI: 10.1016/j.ddtec.2014.03.004
Pinto, M, Digles, D & Ecker, GF 2014, 'Computational models for predicting the interaction with ABC transporters' Drug Discovery Today: Technologies, Bd 12, S. e69-77. DOI: 10.1016/j.ddtec.2014.03.007
Batchelor, C, Brenninkmeijer, CYA, Chichester, C, Davies, M, Digles, D, Dunlop, I, Evelo, CT, Gaulton, A, Goble, C, Gray, AJG, Groth, P, Harland, L, Karapetyan, K, Loizou, A, Overington, JP, Pettifer, S, Steele, J, Stevens, R, Tkachenko, V, Waagmeester, A, Williams, A & Willighagen, EL 2014, Scientific lenses to support multiple views over linked chemistry data. in Lecture Notes in Computer Science: The Semantic Web – ISWC 2014. Bd. 8796, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Bd. 8796, Springer, S. 98-113, Riva del Garda, Italien, 19-23 Oktober. DOI: 10.1007/978-3-319-11964-9_7
Digles, D & Ecker, GF 2011, 'Self-Organizing Maps for In Silico Screening and Data Visualization' Molecular Informatics, Bd 30, Nr. 10, S. 838-846. DOI: 10.1002/minf.201100082
Digles, D, Heiß, E, Dirsch, V & Ecker, G 2011, 'Ligand based screening for insulin mimetic compounds.' Joint Meeting of the Austrian and German Pharmaceutical Societies, Innsbruck, Österreich, 20/09/11 - 23/09/11,.
Digles, D 2011, 'Identification of new insulin mimetic compounds using computational methods.' European School on Medicinal Chemistry, Urbino, Italien, 3/07/11 - 8/07/11,.
Digles, D, Dirsch, V & Ecker, G 2010, 'Ligand based screening tools for identification of insulin receptor activating compounds.' 239th ACS National Meeting, San Francisco, USA / Vereinigte Staaten, 21/03/10 - 25/03/10,.
Digles, D, Dirsch, V & Ecker, G 2009, 'Combined in silico/in vitro screening tools for identification of new insulin receptor ligands'.
Digles, D, Dirsch, V & Ecker, G 2009, 'In silico screening for insulin receptor activating compounds' 7th European Workshop in Drug Design, Siena, Italien, 24/05/09 - 30/05/09,.
Digles, D, Dirsch, V & Ecker, G 2009, 'Docking studies on the insulin receptor' EFMC's Joint Meeting on Medicinal Chemistry 2009, Budapest, Ungarn, 24/06/09 - 27/06/09,.
Digles, D, Dirsch, V & Ecker, G 2009, 'Ligand-based screening tools for insulin receptor activating compounds' 21. Wissenschaftliche Tagung der Österreichischen Pharmazeutischen Gesellschaft, Wien, Österreich, 16/04/09 - 18/04/09,.
Digles, D, Dirsch, V & Ecker, G 2008, 'Classification of insulin receptor activators with self-organizing maps' Drugs of the Future, Bd 33, Nr. Suppl. A.
Digles, D, Ecker, G & Dirsch, V 2008, 'Classification of insulin receptor activators with self-organising maps' XXth International Symposium on Medicinal Chemistry (EFMC-ISMC 2008), Wien, Österreich, 31/08/08 - 4/09/08,.

Department für Pharmazeutische Chemie

Althanstraße 14 (UZA II)
1090 Wien

T: +43-1-4277-55007
F: +43-1-4277-855007