Publications, Patents, Books and Book Chapters
Showing entries 131 - 140 out of 284
2014
Ratnam, J, Zdrazil, B, Digles, D, Cuadrado-Rodriguez, E, Neefs, J-M, Tipney, H, Siebes, R, Waagmeester, A, Bradley, G, Chau, CH, Richter, L, Brea, J, Evelo, CT, Jacoby, E, Senger, S, Loza, MI, Ecker, GF & Chichester, C 2014, 'The Application of the Open Pharmacological Concepts Triple Store (Open PHACTS) to Support Drug Discovery Research', PLoS ONE, vol. 9, no. 12, e115460. https://doi.org/10.1371/journal.pone.0115460
Neudorfer, C, Shanab, K, Jurik, A, Schreiber, V, Neudorfer, C, Vraka, C, Schirmer, E, Holzer, W, Ecker, G, Mitterhauser, M, Wadsak, W & Spreitzer, H 2014, 'Development of potential selective and reversible pyrazoline based MAO-B inhibitors as MAO-B PET tracer precursors and reference substances for the early detection of Alzheimer's disease', Bioorganic & Medicinal Chemistry Letters, vol. 24, no. 18, pp. 4490-4495. https://doi.org/10.1016/j.bmcl.2014.07.085
Michl, J, Scharinger, C, Zauner, M, Kasper, S, Freissmuth, M, Sitte, HH, Ecker, GF & Pezawas, L 2014, 'A multivariate approach linking reported side effects of clinical antidepressant and antipsychotic trials to in vitro binding affinities', European Neuropsychopharmacology, vol. 24, no. 9, pp. 1463-1474. https://doi.org/10.1016/j.euroneuro.2014.06.013
Schöffmann, A, Wimmer, L, Goldmann, D, Khom, S, Hintersteiner, J, Baburin, I, Schwarz, T, Hintersteininger, M, Pakfeifer, P, Oufir, M, Hamburger, M, Erker, T, Ecker, GF, Mihovilovic, MD & Hering, S 2014, 'Efficient modulation of γ-aminobutyric acid type A receptors by piperine derivatives', Journal of Medicinal Chemistry, vol. 57, no. 13, pp. 5602-5619. https://doi.org/10.1021/jm5002277
Hofmaier, T, Luf, A, Seddik, A, Stockner, T, Holy, M, Freissmuth, M, Ecker, GF, Schmid, R, Sitte, HH & Kudlacek, O 2014, 'Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters', Neurochemistry International, vol. 73, no. 1, pp. 32-41. https://doi.org/10.1016/j.neuint.2013.11.010
Smith, D, Artursson, P, Avdeef, A, Di, L, Ecker, GF, Faller, B, Houston, JB, Kansy, M, Kerns, EH, Kramer, SD, Lennernaes, H, van de Waterbeemd, H, Sugano, K & Testa, B 2014, 'Passive Lipoidal Diffusion and Carrier-Mediated Cell Uptake Are Both Important Mechanisms of Membrane Permeation in Drug Disposition', Molecular Pharmaceutics, vol. 11, no. 6, pp. 1727-1738. https://doi.org/10.1021/mp400713v
Pinto, M, Digles, D & Ecker, GF 2014, 'Computational models for predicting the interaction with ABC transporters', Drug Discovery Today: Technologies, vol. 12, pp. e69-e77. https://doi.org/10.1016/j.ddtec.2014.03.007
Ecker, GF 2014, 'Transmembrane drug transporter - taxonomy, assays, and their role in drug discovery', Drug Discovery Today: Technologies, vol. 12, pp. e35-e36. https://doi.org/10.1016/j.ddtec.2014.04.002
Viereck, M, Gaulton, A, Digles, D & Ecker, GF 2014, 'Transporter taxonomy - a comparison of different transport protein classification schemes', Drug Discovery Today: Technologies, vol. 12, pp. e37-e46. https://doi.org/10.1016/j.ddtec.2014.03.004
Carrió, P, Pinto, M, Ecker, G, Sanz, F & Pastor, M 2014, 'Applicability Domain ANalysis (ADAN): a robust method for assessing the reliability of drug property predictions', Journal of Chemical Information and Modeling, vol. 54, no. 5, pp. 1500-1511. https://doi.org/10.1021/ci500172z
Showing entries 131 - 140 out of 284