Open PHACTS (Open Pharmacological Concepts Triple Store) is a knowledge management project of the Innovative Medicines Initiative (IMI), a unique partnership between the European Community and the European Federation of Pharmaceutical Industries and Associations (EFPIA).

The Open PHACTS consortium will create an open innovative platform, Open Pharmacological Space, which will be freely accessible for knowledge discovery and verification. It will also serve other IMI projects, the broader pharmaceutical industry, and other public drug discovery efforts.

Open PHACTS will provide a growing body of data on small molecules, their pharmacological profiles, pharmacokinetics, ADMET data, biological targets and pathways in a semantically interoperable format. Aligning and integrating proprietary and public data sources into a single system is currently a very difficult and time consuming task, repeated across companies, institutes and academic laboratories.

Open PHACTS will develop an integrated system, guided by typical research questions from participating drug discovery teams.

The Open PHACTS consortium comprises of 29 partners from a wide range of backgrounds (Academia, Pharma and Biotech companies) combining expertise in pharmacology, nanopublications, semantic technology, text mining, as well as bio- and cheminformatics.