The RESOLUTE consortium: unlocking SLC transporters for drug discovery

Author(s)
, Giulio Superti-Furga, Tabea Wiedmer, Alvaro Ingles-Prieto, Barbara Barbosa, Enrico Girardi, Ulrich Goldmann, Bettina Gürtl, Kristaps Klavins, Christoph Klimek, Sabrina Lindinger, Eva Liñeiro-Retes, André C Müller, Svenja Onstein, Gregor Redinger, Daniela Reil, Vitaly Sedlyarov, Gernot Wolf, Matthew Crawford, Robert Everley, David Hepworth, Shenping Liu, Stephen Noell, Mary Piotrowski, Robert Stanton, Hui Zhang, Salvatore Corallino, Andrea Faedo, Maria Insidioso, Giovanna Maresca, Loredana Redaelli, Francesca Sassone, Lia Scarabottolo, Michela Stucchi, Paola Tarroni, Sara Tremolada, Helena Batoulis, Andreas Becker, Eckhard Bender, Yung-Ning Chang, Alexander Ehrmann, Anke Müller-Fahrnow, Giulia Banci, Claire Colas, Daniela Digles, Gerhard Ecker, Barbara Füzi, Viktoria Gamsjäger, Melanie Grandits, Riccardo Martini, Florentina Troger
Abstract

The Innovative Medicines Initiative Consortium RESOLUTE has started to develop tools and produce data sets to de-orphanize transporters in the solute carrier protein (SLC) superfamily, thereby lowering the barrier for the scientific community to explore SLCs as an attractive drug target class.

Organisation(s)
Department of Microbiology, Immunobiology and Genetics, Department of Pharmaceutical Chemistry
Journal
Nature Reviews. Drug Discovery
ISSN
1474-1776
DOI
https://doi.org/10.1038/d41573-020-00056-6
Publication date
04-2020
Austrian Fields of Science 2012
Pharmaceutical chemistry
Portal url
https://ucris.univie.ac.at/portal/en/publications/the-resolute-consortium-unlocking-slc-transporters-for-drug-discovery(8dcf5d28-7e0e-411d-bfa5-5eda7ff9a547).html